There is no clear answer as to what causes Outlook from starting in safe mode. What Causes ‘Outlook Failed to Launch in Safe Mode’ Issue? Now that we’ve looked at a few scenarios discussing about the issue, let’s understand what could be the reasons behind it. He further added, he “ cannot even start Outlook in safe mode”. In this instance, the user told that he was unable to open Outlook 2016 after upgrading from Office 2010 to Office 2016. User Instance 2 – Outlook 2016 not opening, not even in Safe Mode And, Outlook failed to open in safe mode as well. In this instance, user said that he received ‘ Outlook has stopped working’ error message when launching the email application. Occurrences of Outlook Failed to Open in Safe Mode User Instance 1 – Outlook won’t start in Safe Mode If you have also encountered such an issue, then this post is for you. You clicked ‘Yes’ in the dialog box, but even the repair didn’t start. Do you want to start repair?įigure 1 - Outlook won’t open in safe mode error message